High mobility group protein hmg-i/hmg-y
WebJan 13, 2010 · The high mobility group A1 (HMGA1, formerly HMG-I/Y) proteins participate in diverse, fundamental cellular processes, including transcriptional regulation, embryogenesis, transformation, cell cycle regulation, differentiation, senescence, viral integration, and DNA repair ( 1 – 22 ). WebThe HMG (high mobility group) proteins are transcription regulators. HMGAs bind to the AT-rich regions of the minor groove of the DNA. HMGA2 is overexpressed in some cancers. It regulates the cell cycle, activates epithelial mesenchymal transition (EMT) and promotes cancer invasion and metastasis.
High mobility group protein hmg-i/hmg-y
Did you know?
Webhigh mobility group protein HMG-I/HMG-Y, high mobility group AT-hook protein 1, high mobility group protein GeneRIFs: Gene References Into Functions distinct loci exist for growth and fatness in the two populations and identified HMGA1 and PLAG1 as strong candidate genes on SSC7 and SSC4, respectively. WebThe HMG-I/Y gene encodes the HMG-I and HMG-Y proteins, which function as architectural chromatin binding proteins important in the transcriptional regulation of several genes. Although increased expression of the HMG-I/Y proteins is associated with cellular proliferation, neoplastic transformation, …
WebMar 6, 2014 · High mobility group (HMG) proteins are the most abundant non-histone chromatin associated proteins. Based on their DNA binding domains, the HMG proteins are subdivided into three families (Figure 1A ): HMGA (containing AT-hooks), HMGB (containing HMG-boxes) and HMGN (containing nucleosomal binding domains) ( Bustin, 2001; Catez … WebNov 27, 1992 · In this paper, we show that both NF-κB and the high mobility group protein I(Y) (HMG I(Y)) are required for virus induction of the human interferon-β (IFN-β) gene. NF-κB binds to the terminal regions of a 10 by regulatory sequence through contacts in the major groove, while HMG I(Y) recognizes the central region of the same sequence through ...
WebThe HMGA (High Mobility Group A) protein family belongs to the same High Mobility Group superfamily of HMGN proteins . Despite distinct families differing in functions and structural domains, all HMG proteins lack any obvious specificity for DNA consensus sequences and compete with different mechanisms with histone H1 for DNA binding, thus ... WebThe high-mobility-group protein HMG-I is a well-characterized nonhistone chromosomal protein that is preferentially expressed in rapidly dividing cells, binds to A T-rich regions of …
WebThe high-mobility-group protein HMG-I is a well-characterized nonhistone chromosomal protein that is preferentially expressed in rapidly dividing cells, binds to A T-rich regions of DNA in vitro, and has been localized to particular regions of mammalian metaphase chromosomes. We isolated eight cDNA clones encoding HMG-I and its isoform HMG-Y ...
WebNov 27, 1992 · Abstract. In this paper, we show that both NF-κB and the high mobility group protein I (Y) (HMG I (Y)) are required for virus induction of the human interferon-β (IFN-β) … how many resonance structures does no2- haveWebThe HMGA (High Mobility Group A) protein family belongs to the same High Mobility Group superfamily of HMGN proteins . Despite distinct families differing in functions and … howdens acrylic worktopsWebMar 30, 1999 · The host-cell architectural protein HMG I(Y) modulates binding of herpes simplex virus type 1 ICP4 to its cognate promoter The productive infection cycle of herpes simplex virus is controlled in part by the action of ICP4, an immediate-early gene product that acts as both an activator and repressor of transcription. howdens adapted kitchensWebApr 3, 2024 · HMG provides family medicine, internal medicine & specialty care to the Tri-Cities area of TN & VA in Kingsport, Bristol, Johnson City & more. ... Holston Medical … howden safancoWebAug 15, 2024 · Gene ID: 746594, updated on 15-Aug-2024. Summary Other designations. high mobility group protein HMG-I/HMG-Y howdens acquires sheridanWebJan 23, 2007 · High mobility group protein HMG-I/HMG-Y Short names HMG-I (Y) Alternative names High mobility group AT-hook protein 1 ( High mobility group protein A1) Gene names Name Hmga1 Organism names Organism Rattus norvegicus (Rat) Taxonomic identifier 10116 NCBI Taxonomic lineage howdens aged brass tapWebNational Center for Biotechnology Information howdens aeg appliances